Events

Sept 24-25, 2018
First Annual IMPRINT Network Meeting

Our first annual full network meeting will be held on the 24th and 25th of September in Kingston upon Thames, Greater London. Click here for more information and registration.

News

Aug 2018
The Advancing Maternal Immunization collaboration (AMI) gap analysis report on RSV

Beate Kampmann, our IMPRINT network PI, and Naor Bar-Zeev, our challenge 6 co-lead, joined 58 other individuals across 25 organizations in 14 countries to publish the AMI gap analysis report on respiratory syncytial virus (RSV) maternal immunization. The Advancing Maternal Immunization collaboration (AMI), coordinated by PATH in collaboration with the WHO, brings together diverse stakeholders from around the world and across immunization and maternal, newborn, and child health programs to identify a pathway to enable informed decision-making and introduction of maternal RSV vaccines, particularly in LMICs, and to provide tools to help decision-makers, implementers, researchers, and others navigate that pathway successfully.

Maternal vaccines are being developed for RSV and could be available in a few years, underscoring a need to establish an environment poised for vaccine decision-making and introduction now.

Aug 2018
Publication update

We will regularly highlight publications from IMPRINT members and/or with relevance to the issue of maternal immunization in this section – please find current papers below:

  • Beyond Passive immunity: Is There Priming of the Fetal Immune System Following Vaccination in Pregnancy and What Are the Potential Clinical Implications David R. Wilcox and Chrissie E. Jones. Front. Immunol. 9:1548. doi: 10.3389/fimmu.2018.01548

    Prof. Chrissie Jones is the Co-director of IMPRINT and challenge 2 co-lead, Dr Christopher Wilcox is one of our IMPRINT members.

  • Professor Heidi J. Larson, Director of the Vaccine Confidence Project at the London School of Hygiene & Tropical Medicine, where she is a Professor of Anthropology, Risk and Decision Science and our IMPRINT challenge 4 co-lead joined a “A Conversation About the Current State of Vaccines” at the London International Development Center.

Aug 2018
Funding opportunities – Newton Fund and International Development Research Center OWSD/UNESCO fellowships

The following funding opportunities just recently opened for early to mid-career researchers:

  • The Newton Fund Advanced Fellowships and Mobility grants are now open.

    Newton Advanced Fellowships provide early to mid-career international researchers who already have a track record with an opportunity to develop their research strengths and capabilities, and those of their group or network, through training, collaboration and visits with a partner in the UK. Fellowships awarded by the British Academy are currently only available for researchers in the following countries: China, Mexico, South Africa, Thailand and Turkey.

    Find all details at:  https://www.britac.ac.uk/newton-advanced-fellowships

    Closes on Wednesday, 5th of September 2018.

  • In partnership with UNESCO’s Organization for Women in Science for the Developing World (OWSD), The International Development Research Center (IDRC) just announced the first call for applications for the new Early Career Women Scientists (ECWS) fellowships.

    Fellowships with a value of up to US$50,000 each will be awarded to women scientists from countries where the capacity for science and technology is lagging; who have completed their PhD in science, technology, engineering, or mathematics; and employed at an academic or scientific research institute in one of the eligible countries.

    Closes on Friday, 31st of August 2018.

July 2018
Two new fellowship and six new pump priming grants awarded!

Congratulations our new awardees and their collaborating partners! Titles and lay summaries of the projects can be found on our projects website.

July 2018

The awards provide up to £25,000 over one year to support collaborations between developing countries and the UK and to hold networking events aimed at addressing global challenges. The scheme allows researchers from across disciplines and from developing countries and the UK to hold networking events, to forge new links and generate innovative transdisciplinary research ideas to address global challenges.

Key dates: Round 3 of the scheme is now open, and will close on 8 August 2018.

Jun 07, 2018
IMPRINT – the first year in review
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Time flies! On May 22nd 2018, our IMPRINT Board members came together in London to review the first completed year of the network’s activities, summarize the status of scientific progress in the six thematic challenges, critically assess the network’s strengths, weaknesses, threats and opportunities, and jointly plan ahead.

Twelve months down the road, all structures are in place and fully functional, the second round of applications under the pump priming and fellowship schemes is already being reviewed, candidates selected in the first calls have started their projects, and preparations for the first full network meeting in September are nearing completion. Additional calls for Public Engagement activities will be published soon, and first selected training opportunities are about to be communicated to the continuously increasing network membership.

Excited about so much progress in year one, we are now looking forward to expanding the set of activities even further in year number two.

May 25, 2018
IMPRINT Research Session at ESPID – Malmö, 31st of May

Thousands of clinicians, researchers, residents, and students will come together for the annual Meeting of the European Society for Paediatric Infectious Diseases on May 28th – June 2nd in Malmö, Sweden.

Join our IMPRINT Co-PI Chrissie Jones for our Research Session on Thursday, May 31, 2018 at 14:00-15:30 (Room: Romeo).

In addition, Dr Chrissie Jones will also be available during the “Meet the Professor” Session on Thursday; May 31st at 7:00-7:25 (Session code ET15) and present “a randomized controlled trial comparing two pertussis-containing vaccines in pregnancy and vaccine responses in UK mothers and their infants (Immunizing Mums Against Pertussis, IMAP2), Thursday, May 31st from 10:00-10.15 (Session code SET01).

Feb 27, 2018
Additional funding for IMPRINT from The Industry Strategy Challenge Fund

We are happy to announce that IMPRINT has been awarded a £599,920 supplement under The Industrial Challenge Strategy Fund (ICSF), which will allow us to bring additional and diverse pump-priming activities to our Network and to enhance collaborations between industry and academic researchers.

The ICSF aims to bring together the UK’s world-leading research with business to meet the major industrial and societal challenges of our time, including leading-edge healthcare.

With the additional funding, we are not only able to fund more exciting research projects, but also to introduce special industry-academia-sessions at our network meetings to spark and strengthen cross-sectoral collaboration. In addition, we will produce educational materials to explain our science to lay audiences, give out IMPRINT Public Engagement Awards, and offer transferable skills training for our members at different levels – particularly to young scientists.

Feb 25, 2018
New members

We have just added our 100th member to your network. Our members come from 25 different countries. Join us today and become eligible for pump priming and fellowship funding. You can help us tackle the challenges in the best use of vaccines in pregnancy and newborns.

Feb 23, 2018
2 new Fellowship Grants awarded

Congratulations to our first two fellowship awardees and their collaborating partners whose projects will start from May 2018!

Dr Alansana Darboe from the Vaccine & Immunity Theme, Medical Research Council Unit The Gambia at the London School of Hygiene and Tropical Medicine will be leading the project "Understanding interactions between Maternal IgG and Neonatal Innate Immune Cells (MINIC)" that will be implemented together with the two Co-PIs Prof Tobias Kollmann from the Department of Pediatrics at the University of British Columbia, Canada and Prof. Arnaud Marchant from the Institute for Medical Immunology, Université Libre de Bruxelles, Belgium.

Dr Shadia Khandaker from the Department of Clinical Infection, Microbiology and Immunology, Institute of Infection and Global Health at the University of Liverpool will be leading the project “Towards the understanding of anti-Group B Streptococcus (GBS) protective immunity: characterisation of maternal sera in high- vs. low- GBS prevalence countries using humanised mice” that will be implemented together with the three Co-PIs Prof. Aras Kadioglu and Prof Neil French from the University of Liverpool and Prof. Samir Kumar Saha from the Child Health Research Foundation (CHRF) and the Bangladesh Institute of Child Health Research Foundation, Dhaka Shishu (Child) Hospital, Bangladesh.

Feb 15, 2018
Maternity & Midwifery Festival

IMPRINT was promoted at the first London Maternity & Midwifery Festival that took place on February 13th 2018 with over 1600 participants. This national professional festival, with leadership speakers and exhibitions, is to be held annually to highlight developments in maternity and midwifery across the South East of the United Kingdom.

Our IMPRINT network member Beth Holder and a team from London School of Hygiene and Tropical Medicine attended the event to promote MatImms, a free Smartphone App designed by leading experts of paediatric infectious diseases at London School of Hygiene and Tropical Medicine that aims to improve vaccine information available to pregnant women, enabling them to make informed choices and encourages vaccination in pregnancy to protect newborn babies from preventable infections.  MatImms collaborate with pregnant women alongside academic, clinical and policy partners such as Public Health England and antenatal services, in the UK and globally through the Centre for International Child Health.

Matimms is led by Professor Beate Kampmann, a world leader in maternal immunization at Imperial college and one of our IMPRINT founders.

Jan 15, 2018
Publication update

We will regularly highlight publications from IMPRINT members and/or with relevance to the issue of maternal immunization in this section – please find current papers below:

  • “Failure to thrive: Case definition & guidelines for data collection, analysis, and presentation of maternal immunisation safety data

    Elizabeth Ross, Flor M. Munoz, Bassey Edem, Cassandra Nan,d Fyezah Jehan, Julie Quinn, Tamala Mallett Moore, Sanie Sesay, Hans Spiegel, Librada Fortuna, Sonali Kochhar, Jim Buttery, for The Brighton Collaboration Failure to Thrive Working Group

    Vaccine. 2017 Dec 4;35(48 Pt A):6483-6491. doi: 10.1016/j.vaccine.2017.01.051

    Co-authored by IMPRINT founding member and challenge 5 co-lead Dr Sonali Kochhar and IMPRINT member Dr Flor M. Munoz.

  • “Factors Affecting the FcRn-Mediated Transplacental Transfer of Antibodies and implications for vaccination in Pregnancy”

    Christopher R. Wilcox, Beth Holder and Christine E. Jones

    Front Immunol. 2017; 8: 1294.  Published online 2017 Oct 13. doi:  10.3389/fimmu.2017.01294

    Professor Chrissie Jones is the Co-director of IMPRINT and co-lead of challenge 2 together with Dr Beth Holder. Dr Christopher Wilcox is one of our IMPRINT members.

  • “Immunization in pregnancy clinical research in low- and middle-income countries – Study design, regulatory and safety considerations”

    Sonali Kochhar, Jan Bonhoeffer, Christine E. Jones, Flor M. Muñoz, Angel Honrado, Jorgen Bauwens, Ajoke Sobanjoter Meulen, Steven Hirschfeld

    Vaccine. 2017, Volume 35, Issue 48, Part A

    Authored by our IMPRINT founding member and challenge 5 co-lead Dr Sonali Kochhar and co-authored by Dr Chrissie Jones, Co-director of IMPRINT and co-lead of challenge 2 as well as our IMPRINT members Dr Flor M. Munoz and Jorgen Bauwens.

    In case you are interested in a detailed overview about Case definition & guidelines for data collection, analysis, and presentation of immunization safety data, please refer to these publications by Dr Sonali Kochhar and other IMPRINT network members.

Jan 12, 2018
Ethics of maternal immunization:

The ethics of maternal immunization is a topic that has been addressed in the following three publications that we want to share with you:

  • Protected to death: systematic exclusion of pregnant women from Ebola virus disease trials
    Melba F. Gomes, Vânia de la Fuente-Núñez, Abha Saxena and Annette C. Kuesel
    Reproductive Health 2017, 14(Suppl 3):172 doi: 10.1186/s12978-017-0430-2
  • Ethics of maternal vaccination- Involvement of women is critical in establishing guidelines
    A. T. Chamberlain, J. V. Lavery, A. White, S. B. Omer
    Science 27 Oct 2017 Vol. 358 (6362), 452-453. DOI:10.1126/science.aao4219 (you need to have a Science account in order to access the publication)
  • Maternal immunisation: ethical issues
    Marcel Verweij, Philipp Lambach, Justin R Ortiz, Andreas Reis
    Lancet Infect Dis 2016; 16: e310–14 DOI: 10.1126/science.aao4219
Jan 10, 2018
New vaccines to protect babies as early as possible

Paul Heath, IMPRINT Executive Board member, discussed the potential of maternal vaccination to protect mothers, fetuses and infants in their first weeks of life and how to further increase their positive impact in Vaccines Today:

“To improve antenatal immunization, we need new strategies to encourage vaccination, ongoing professional education for healthcare providers, and to make maternal vaccination a routine item in women’s healthcare.”

Dec 8, 2017
Three new Pump Priming Grants awarded

Congratulations to our first three pump priming awardees and their collaborating partners whose projects will start in spring 2018!

Dr Qibo Zhang from the Institute of Infection and Global Health, University of Liverpool will be leading the project "Elucidating the effect of maternal immunisation on the subsequent development of T cell response following pertussis vaccination in infants" that will be implemented together with the two Co-PIs Prof. Elke Leuridan from the Centre for the Evaluation of Vaccination, Vaccine & Infectious Diseases Institute, University of Antwerp, Belgium and Prof. Yong Poovorawan from the Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Thailand.

Simon Gwapa Kimuda from the Department of Immunomodulation and Vaccines, Medical Research Council/UVRI Uganda Research Unit on AIDS, will be using in vitro mycobacterial growth inhibition assays as a tool to assess functional immune responses induced by VPM1002 vaccination in infants.
He will be working with Prof. Alison Elliott, Head of Immunomodulation and Vaccines Programme, Medical Research Council/UVRI Uganda Research Unit on AIDS and Prof. Gerhard Walzl, Head of the Department of Biomedical Sciences, Stellenbosch University, South Africa.

Dr Sudaxshina Murdan from the UCL School of Pharmacy, University College London, will work on oral vaccines which generate immune responses in the vagina and prevent mother-to-baby transmission of infections during birth.
In this project she will be collaborating with Prof Abdul Basit from the UCL School of Pharmacy, University College London and Dr Fatme Mawas from the National Institute for Biological Standards and Control (NIBSC), UK.

All selected projects address key challenges of IMPRINT and include collaborations between HIC and LMIC countries to foster and strengthen our maternal vaccine network. They will be funded with a max of £70,000 per project and for a duration of up to 12 months. Full abstracts and further details will be published here soon.

Dec 5 2017
Joint stand of all five vaccine networks at the British Society for Immunology Congress 2017 in Brighton
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Our IMPRINT network manager, Dr. Claudia Schacht, together with our sister Network Managers from the VALIDATE Network (Vaccine development for complex intracellular neglected pathogens), IntVetVac (the International Veterinary Vaccinology Network), HIC-Vac (The Human Challenge Model Network) and BactiVac (the Bacterial Vaccines Network) joined forces during the British Society for Immunology (BSI) meeting in Brighton from 4-7 December 2017 to promote the networks and currently open pump priming and fellowship calls. The team of managers was supported by BSI President Peter Openshaw and MRC Programme Manager Martin Broadstock in their aim of spreading the word and raising awareness of the networks and their activities.

The BSI Congress is the largest national immunology Congress in Europe and was attended by over 1,250 speakers, presenters, sponsors, exhibitors and delegates – all potential new members of one or several of our networks.

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